Jiaqi Guo
Jiaqi's PhD research focuses on AI-aided design and synthesis of small-molecule inhibitors targeting BTK (Bruton’s tyrosine kinase).
Chemistry PhD student
School of Chemical and Physical Sciences
Profile
I am a full-time PhD student in the School of Chemical and Physical Sciences, focusing on early-stage drug discovery. My research centres on the design of Bruton’s tyrosine kinase (BTK) inhibitors, combining synthetic chemistry with computational techniques to guide optimisation and improve selectivity. My goal is to contribute to the development of next-generation BTK inhibitors through iterative design, testing, and refinement.
I hold a Master’s degree in Pharmaceutical Chemistry from Newcastle University in the UK and a Bachelor’s degree in Chemical Engineering. Before starting my PhD, I worked for three years in drug discovery, gaining hands-on experience in organic synthesis and analytical techniques. This background provides me with a solid foundation for my current research at the interface of synthetic and computational chemistry.
Qualifications
Master of Drug Chemistry in Pharmaceutical Chemistry, Newcastle University
Bachelor of Science in Chemical Engineering
Research interests
My research interests lie in the integration of synthetic chemistry and computer-aided drug design (CADD) for the discovery of small-molecule kinase inhibitors.
PhD topic
AI-aided design and synthesis of small-molecule inhibitors targeting BTK (Bruton’s tyrosine kinase)
Supervisor
Associate Professor Joanne Harvey, School of Chemical and Physical Sciences