Publications Susan Schenk
Selected Publications by Susan Schenk
For a full list of Susan's publications visit her Google Scholar profile.
On this page:
2014 - 2016 Publications
Lee L, Goodman L, Fourie C, Schenk S, Leitch B, Montgomery JM (2016) AMPA receptors as therapeutic targets for neurological disorders. Advances in Protein Chemistry and Structural Biology, 103:203-261.
Aronsen D, Bukholt N, Schenk S. (2016) Repeated administration of the 5-HT1B/1A agonist, RU 24969, facilitates the acquisition of MDMA self-administration: Role of 5-HT1A and 5-HT1B receptor mechanisms. Psychopharmacology, 233:1339-1347.
Webster J, Harper D, Schenk S. (2016) Analysis of the Acquisition of Drug Discrimination Reveals Differences Between a High vs Low Training Dose of ±3,4-methylenedioxymethamphetamine (MDMA). Journal of Drug and Alcohol Research, in press, 5: art235976. doi:10.4303/jdar/235976
Aronsen D, Schenk S (2016) MDMA self-administration fails to alter the behavioral response to 5-HT1A and 5-HT1B agonists. Psychopharmacology, 233:1323-1330.
Schenk S, Foote J, Aronsen D, Bukholt N, Van de Wetering R, Webster J. (2016) Serotonin antagonists fail to alter MDMA self-administration in rats. Pharmacology Biochemistry and Behaviour, 148:38-45.
Schenk S, Bradbury S (2015) Persistent sensitization to the locomotor activating effects of MDMA following MDMA self-administration in rats. Pharmacology Biochemistry and Behaviour, 132:103-107.
Schenk S, Aronsen D. (2015) Contribution of Impulsivity and Serotonin Receptor Neuroadaptations to the Development of an MDMA (“ecstasy”) Substance Use Disorder, in Current Topics in Behavioral Neuroscience: The Misuse of Licit and Illicit Drugs in Psychopharmacology Susan Schenk, Suzanne Nielson, Raimondo Bruno (Eds), Springer, DOI 10.1007/7854_2015_421
Oakly AC, Brox BW, Schenk S, Ellenbroek BA (2014) A genetic deletion of the serotonin transporter greatly enhances the reinforcing properties of MDMA in rats. Molecular Psychiatry, 19:534-35.
Bradbury S, Bird J, Colussi-Mas J, Mueller M, Ricaurte G, Schenk S (2014) Acquisition of MDMA self-administration: pharmacokinetic factors and MDMA-induced serotonin release. Addiction Biology, 19:874-84.
Harper, DN, Langen A-L, Schenk S. (2014) A 3-lever discrimination procedure reveals differences in the subjective effects of low and high doses of MDMA. Pharmacology Biochemistry Behavior, 116:9-15.
Aronsen D, Webster J, Schenk S (2014) RU24969-produced adipsia and hyperlocomotion: differential role of 5HT1A and 5HT1B receptor mechanisms. Pharmacology Biochemistry and Behaviour, 124:1-4
2011 - 2013 Publications
Bird J1, Schenk S. (2013) Contribution of impulsivity and novelty-seeking to the acquisition and maintenance of MDMA self-administration. Addiction Biology. 18(4):654-64
Do, J, Schenk S. (2013) MDMA self-administration decreases tissue levels of serotonin: Effects of exposure levels and withdrawal times. Addiction Biology. 18:441-447
Schenk, S., Abraham B, Aronsen D, Colussi-Mas J, Do J, Jones K. (2013) Effects of repeated exposure to MDMA on 5HT1a autoreceptor function: Behavioral and neurochemical responses to 8-OHDPAT. Pychopharmacology. 227:355–361
Oakly AC, Brox BW, Schenk S, Ellenbroek BA (2013) A genetic deletion of the serotonin transporter greatly enhances the reinforcing properties of MDMA in rats. Molecular Psychiatry, doi: 10.1038/mp.2013.75Bradbury S, Bird J, Colussi-Mas J, Mueller M, Ricaurte G, Schenk S (2013)Acquisition of MDMA self-administration: pharmacokinetic factors and MDMA-induced serotonin release. Addiction Biology. doi:10.1111/adb.12069
Do, J, Schenk S. (2012) Self-administered MDMA produces dose- and time-dependent serotonin deficits in the rat brain. Addiction Biology, 18(3):441-7Bradbury S, Gittings D, Schenk S (2012)Repeated exposure to MDMA and Amphetamine: Sensitization, cross sensitization and response to dopamine D1- and D2-like agonists. Psychopharmacology. 223:389-399.
Morani AS, Schenk S, Prisinzano TE, Kivell B (2012) Single injection of novel kappa opioid receptor agonist salvinorin A attenuates expression of cocaine induced behavioral sensitization in rats. Behavioural Pharmacology. 23:162-170
Bird J, Schenk S. (2012) Contribution of impulsivity and novelty seeking to the acquisition and maintenance of MDMA self-administration. Addiction Biology, doi: 10.1111/j.1369-1600.2012.00477.x
Schenk S, Colussi-Mas J, Do J, Bird J. (2012) Profile of MDMA Self-Administration from a Large Cohort of Rats: MDMA Develops a Profile of Dependence with Extended Testing. Journal of Drug and Alcohol Research. 1: doi:10.4303/jdar/235602
Ali SF, Onaivi ES, Dodd P, Cadet JL, Schenk S, Koob GF. (2011) Understanding the global problem of drug addiction is a challenge for IDARS scientist. Current Neuropharmacology. 9:2-7
Harper, D.N., Crowther, A., & Schenk, S. (2011). A Comparison of MDMA and Amphetamine in the Drug Discrimination Paradigm. The Open Addiction Journal. 4, 24-25
Schenk S, Gittings D, Colussi-Mas, J. (2011) Dopaminergic mechanisms of reinstatement of MDMA-seeking behavior in rats. British Journal of Pharmacology. 162(8):1770-1780
Schenk S, Harper DN, Do J. (2011). Novel object recognition memory: measurement issues and effects of MDMA self-administration following short inter-trial intervals. Journal of Psychopharmacology. 25:1045-1052
Schenk, S. (2011) MDMA abuse as an example of dopamine neuroplasticity. Neurosci Biobehav Rev, 35:1203-1218Carati, C., Schenk, S. (2011)Role of D1- and D2-like receptor mechanisms in drug seeking following methamphetamine self-administration in rats. Pharmacology Biochemistry and Behaviour. 98:449-454
2007 - 2010 Publications
Brennan KA, Carati C, Lea RA, Fitzmaurice PS, Schenk S. (2010) Role of D1- and D2-like receptors in 3,4-methylenedioxymethamphetamine and methamphetamine self-administration in rats. Behavioural Pharmacology. 20:688-194.
Colussi-Mas J, Wise R, Howard A and Schenk S. (2010) Drug-seeking in response to a priming injection of MDMA in rats: relationship to initial sensitivity to self-administered MDMA and dorsal striatal dopamine. Int. J. Neuropsychopharmacology. 25:1-13.
Kivell B, Day D, Bosch P, Schenk S, Miller J. (2010) MDMA causes a p38-mitogen-activated protein kinase-independent redistribution of serotonin transporter from the cell-surface to intracellular vesicles. Neuroscience. 168:82-95.
Brennan KA, Colussi-Mas J, Carati C, Lea RA, Fitzmaurice PS, Schenk S. (2010) Methamphetamine self-administration and the effect of contingency on monoamine and metabolite tissue levels in the rat. Brain Research. 1317:137-146.
Jones K, Brennan KA, Colussi-Mas J, Schenk S. (2010) Tolerance to 3,4-methylenedioxymethamphetamine is associated with impaired transporter mediated serotonin release. Addiction Biology. 15:289-298.
Ali SF, Onaivi ES, Dodd P, Cadet JL, Schenk S, Koob GF. (2010) Understanding the global problem of drug addiction is a challenge for IDARS scientist. In press Current Neuropharmacology.
Schenk S, Gittings D, Colussi-Mas, J. (2010) Dopaminergic mechanisms of reinstatement of MDMA-seeking behavior in rats. In press British Journal of Pharmacology.
Schenk S, Harper DN, Do J. (2010) Effects of MDMA self-administration in rats on novel object recognition following short inter-trial intervals. In press J. Psychopharmacology
Schenk, S. (2009) MDMA self-administration in laboratory animals: A summary of the literature and proposal for future research. Neuropsychobiology, 60:130-136.
Morani AS, Kivell B, Prisinzano TE and Schenk S. (2009) Effect of kappa-opioid receptor agonists U69593, U50488H, spiradoline and salvinorin A on cocaine-induced drug-seeking in rats. Pharmacology Biochemistry and Behaviour. 94:244-249
Johnstone A, Brennan K, Schenk S, Kennedy M, Lea R, Fitzmaurice P. (2007) Benzylpiperazine (BZP) a recreational substance or drug of abuse? J. Psychopharmacology. 21:888-894
Brennan K, Johnstone A, Fitzmaurice P, Lea R, Schenk S. (2007) Chronic benzylpiperazine (BZP) exposure produces behavioral sensitization and cross sensitization to methamphetamine (MA). Drug and Alcohol Dependence. 88:204-213.
Schenk, S. Hely, L., Gittings, D., Lake, B., Daniela, E., and Mash DC (2007) MDMA self-administration in rats: Acquisition, progressive ratio responding and serotonin transporter binding. Eur J Neuroscience. 26:3229-3236.
Brennan KA, Lake B, Hely LS, Jones K, Gittings G, Colussi-Mas J, Fitzmaurice PS, Lea Ra, Schenk S. (2007) N-benzylpiperazine (BZP) has characteristics of a drug of abuse. Behavioural Pharmacology. 18:785-790.
Runyon S, Navarro H, Cook CE, Kepler J, and Schenk S Synthesis and Testing of Neuroactive Steroids as Allosteric Modulators of GABAA Receptors. CPDD, June 2007
Johnstone, AC, Brennan, KA, Schenk, S, Kennedy MA, Fitzmaurice PS and Lea RA. (2007) Neurogenomics of drugs of abuse: Methamphetamine and benzylpiperazine. IBRO
Schenk, S. (2007) Drug primes that reinstate extinguished MDMA and cocaine self-administration. IBRO
Kivell BM, Day D., Schenk S., and Miller JH, (2007) The serotonin transporter is redistributed following MDMA (ecstasy) exposure. IBRO
Schenk, S. (2007) Dopaminergic mechanisms of MDMA-produced drug-seeking. AWCBR
Mandt BH, Schenk S, Zahniser NR, and Allen RM. (2007, 2008) Low dose cocaine self-administration in low and high cocaine locomotor responding. adu11